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Bioclinic Naturals EstroVantage Em (90 Vegetarian Capsules)

Bioclinic Naturals EstroVantage Em (90 Vegetarian Capsules)

SKU 2226
$48.23
Enhances estrogen processing and supports optimal estrogen balance
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Bioclinic Naturals EstroVantage Em (90 Vegetarian Capsules)
Product Details
Weight: 0.60 lbs

Bioclinic Naturals EstroVantage Em (90 Vegetarian Capsules)

  • Assists in maintaining hormonal harmony for women
  • Includes cruciferous plant extracts to steer estrogen metabolites toward healthy pathways
  • Modulates crucial signaling pathways such as Nrf2 and NF-κB
  • Free from artificial dyes, preservatives, sweeteners, as well as dairy, gluten, wheat, and yeast

Introducing Bioclinic Naturals EstroVantage EM — a potent supplement featuring 90 Vegetarian Capsules designed to support women’s hormonal health. Crafted with a blend of botanical compounds, this formula aims to optimize estrogen metabolism, helping to balance hormone levels naturally. Each capsule includes extracts from cruciferous vegetables rich in glucosinolates, which play a crucial role in directing estrogen metabolites toward less harmful forms, thereby supporting healthier estrogen pathways.

Beyond its impact on estrogen processing, EstroVantage EM targets vital cellular signaling mechanisms such as Nrf2 and NF-κB, which are instrumental in managing oxidative stress and inflammatory responses. This dual action not only promotes hormonal equilibrium but also contributes to cellular resilience and aging gracefully. Regular use may help ease menopausal symptoms like hot flashes, mood swings, and fatigue, empowering women to maintain vitality during hormonal transitions.

Formulated with a variety of plant-based antioxidants and phytochemicals, EstroVantage EM further supports detoxification and reduces inflammation. It features indole-3-carbinol (I3C) and 3,3’-diindolylmethane (DIM) from broccoli, sulforaphane, and other bioactive compounds such as silymarin from milk thistle, green tea polyphenols, lycopene, turmeric, rosemary, and calcium D-glucarate. These ingredients have been associated with promoting healthy estrogen metabolism, lowering carcinogenic risks, and enhancing the body's natural defense mechanisms.

Free from artificial colors, preservatives, sweeteners, dairy, gluten, wheat, and yeast, EstroVantage EM offers a clean, plant-based approach to supporting women’s hormonal health. Whether you're seeking menopause relief, hormone balance, or overall wellness, this supplement is designed to provide comprehensive support for your unique health journey.


Postmenopausal women often face challenges such as low estradiol levels, elevated estrone, and compromised estrogen detoxification. Typical patterns include high estrone, low levels of 2-methoxyestrone, and an unfavorable 2-methoxyestrone to 2-hydroxyestrone (2-OH-E1) ratio. The ingredients listed below are formulated to support liver detoxification (both Phase I and Phase II), decrease harmful estrogen metabolites, and help restore a healthy balance in estrogen pathways.

Ingredients and Specifications

Ingredient Amount Per Serving
Calcium D-Glucarate (d-Glucaric Acid Calcium Salt) 225 mg
Indole-3-Carbinol (3-Hydroxymethylindole) 225 mg
Green Tea Extract (Camellia sinensis) (leaf) (80% Catechins, 45% EGCG*, <1% Caffeine) 150 mg
Tomato Extract (Lycopersicon esculentum) (fruit) (5% Lycopene) 150 mg
Broccoli Powder (Brassica oleracea var. italica) (aerial) (0.36% Sulforaphane) 82.5 mg
DIM (3,3’-Diindolylmethane) 75 mg
Turmeric Extract (Curcuma longa) (rhizome) (95% Curcuminoids) 75 mg
Milk Thistle Extract (Silybum marianum) (seed) (50–60% Silymarin) 75 mg
Rosemary 6:1 Extract (Rosmarinus officinalis) (leaf) 37.5 mg

Other Ingredients

Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica.

Green Tea Extract (96 mg)

- Mechanism: Rich in EGCG, which inhibits aromatase and promotes 2-hydroxylation of estrone; also enhances COMT enzyme activity for methylation of 2-OH-E1 to 2-methoxyestrone.

- Benefit: Aids in reducing overall estrogen burden and boosts beneficial 2-methoxyestrone levels.

Catechins (54 mg)

- Mechanism: Active compounds in green tea that work synergistically to inhibit estrogen synthesis and support detoxification pathways.

- Benefit: Amplify the positive effects of green tea extract on estrogen metabolism.

Rosemary Leaf Extract (38 mg)

- Mechanism: Stimulates CYP1A1 and CYP1B1 enzymes in the liver, enhancing 2-hydroxylation of estrogens.

- Benefit: Promotes safer estrogen metabolism and increases production of protective 2-OH-E1.

Turmeric Extract (75 mg)

- Mechanism: Curcumin enhances COMT enzyme activity for methylation and has anti-inflammatory properties.

- Benefit: Supports Phase II detoxification, particularly methylation, helping to improve estrogen balance.

Milk Thistle Extract (75 mg)

- Mechanism: Boosts glutathione production, strengthening liver detoxification capacity across Phase I and II.

- Benefit: Facilitates efficient processing and clearance of estrogens from the body.

Broccoli Extract (83 mg) – Brassica oleracea italica

- Mechanism: Provides glucosinolates that convert into I3C and sulforaphane, activating CYP1A1 enzyme.

- Benefit: Critical for shifting estrogen metabolism toward the protective 2-hydroxy pathways.

Tomato (150 mg)

- Mechanism: Contains lycopene, a potent antioxidant that helps reduce oxidative stress from estrogen metabolism.

- Benefit: Supports overall cellular health, especially in estrogen dominance scenarios.

Calcium D-Glucarate (225 mg)

- Mechanism: Inhibits beta-glucuronidase, preventing reabsorption of estrogens in the gut, and supports Phase II glucuronidation.

- Benefit: Promotes estrogen elimination and reduces systemic estrogen levels.

DIM (75 mg)

- Mechanism: Encourages 2-hydroxylation of estrogens while reducing the formation of harmful 16α- and 4-hydroxy estrogen metabolites.

- Benefit: Supports safer estrogen detoxification and improves key metabolite ratios.

Indole-3-Carbinol

- Mechanism: Precursor to DIM; enhances CYP1A1 activity and may reduce estrogen receptor alpha activity.

- Benefit: Further promotes 2-hydroxylation pathways, complementing DIM’s effects for balanced estrogen metabolism.


This formulation aims to optimize estrogen detoxification, support liver health, and restore hormonal balance in postmenopausal women experiencing estrogen dominance and related metabolic challenges.

Suggested Usage

3 capsule per day taken with food or as directed by a health care professional. Consult a health care professional for use beyond 12 weeks.

Allergens:

Contains no artificial colors, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.

Warnings

Avoid use if you are pregnant or nursing, or if you have an iron deficiency. If you have gallstones, bile duct obstructions, stomach ulcers, or excess stomach acidity, or are taking medications, consult a healthcare professional before use. Prior to use, seek medical advice if you are trying to conceive, experiencing low estrogen levels or symptoms associated with low estrogen, have or are at risk for cancer, are using blood thinners or antiplatelet drugs, or have a liver condition. Discontinue use and seek medical attention if you notice signs of liver issues such as jaundice (yellowing of the skin or eyes), abdominal pain, dark urine, sweating, nausea, unusual fatigue, or loss of appetite. Cases of liver injury linked to products containing green tea extract have been sporadically reported both in Canada and internationally. Allergic reactions or hypersensitivity may occur; if so, stop use immediately. Keep out of reach of children.

How Supplied

Bioclinic Naturals EstroVantage Em is available in bottles of 90 Vegetarian Capsules.

Additional Information

If you're unsure whether Bioclinic Naturals EstroVantage Em is right for your health goals, contact us at 888-932-5256 for more information.

If you are interested in getting program recommendations from an Herbalist, click here to submit the client questionnaire.

Frequently Asked Questions

Q1: What is EstroVantage EM, and how does it support women’s health?

A: EstroVantage EM is a plant-based supplement formulated to support hormone balance in women. It promotes healthy estrogen metabolism, helps reduce menopausal symptoms, and supports overall hormonal harmony through natural botanical compounds.

Q2: How does EstroVantage EM help with estrogen metabolism?

A: The supplement contains cruciferous vegetable extracts rich in glucosinolates, which direct estrogen metabolites toward less carcinogenic forms. Ingredients like indole-3-carbinol (I3C), DIM, and sulforaphane work together to optimize estrogen pathways and promote a healthier estrogen profile.

Q3: Can EstroVantage EM help with menopausal symptoms?

A: Yes, many women experience relief from hot flashes, mood swings, and fatigue when using EstroVantage EM, as it supports hormonal balance and overall wellness during menopause.

Q4: What are the key signaling pathways targeted by this supplement?

A: EstroVantage EM targets critical cellular pathways such as Nrf2 and NF-κB, which are involved in managing oxidative stress, inflammation, and cellular aging, helping promote cellular health and resilience.

Q5: Are there any anti-inflammatory benefits associated with EstroVantage EM?

A: Absolutely. The supplement includes ingredients like silymarin, green tea polyphenols, turmeric, rosemary, and calcium D-glucarate, which work to reduce inflammation and support detoxification processes.

Q6: Is this supplement suitable for individuals with food sensitivities?

A: Yes. EstroVantage EM is free from artificial colors, preservatives, sweeteners, dairy, gluten, wheat, and yeast, making it suitable for those with common food sensitivities.

Q7: Who can benefit from taking EstroVantage EM?

A: Women seeking natural support for hormonal balance, menopause relief, or those looking to improve estrogen metabolism and reduce carcinogenic risks can benefit from this supplement.

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