Tesamorelin (10mg) – Lyophilized Research Peptide

Targeted visceral fat support, GH/IGF-1 pathway activation, and recovery-focused body recomposition

Tesamorelin is a synthetic growth hormone–releasing hormone (GHRH) analog designed to stimulate your body’s own pulsatile release of growth hormone (GH) from the pituitary. Unlike direct HGH injections, Tesamorelin works upstream—supporting the GH → IGF-1 signaling pathway while preserving the body’s natural feedback mechanisms.

Tesamorelin is best known clinically for its prescription use in specific settings related to visceral abdominal fat. In wellness and physique protocols, it’s often chosen for recomposition goals—especially when the focus is reducing “deep” belly fat while supporting lean tissue retention and recovery.

Key Benefits

• Supports GH/IGF-1 signaling in a more physiologic, pulsatile pattern
• Often used to support reductions in visceral abdominal fat (deep belly fat) alongside diet and training
• Supports lean muscle retention during cutting or recomp phases
• May support recovery capacity and connective tissue adaptation over time (collagen signaling)
• Frequently used in longevity-style protocols focused on metabolic health and body composition

How It Works

Tesamorelin binds to GHRH receptors in the anterior pituitary, triggering a pulse of endogenous growth hormone. That GH pulse can increase downstream IGF-1, which is often discussed as a key mediator for body composition and recovery-related outcomes.

Because it stimulates your own GH release rather than replacing GH directly, Tesamorelin is commonly positioned as a more “feedback-friendly” approach compared with exogenous HGH use.

Typical Dosage & Administration (Informational)

• Commonly referenced dose: 1 mg daily
• Timing: 30–60 minutes before bed, ideally fasted (avoid eating for ~1 hour before/after when possible)
• Administration: subcutaneous injection (abdomen is commonly referenced; rotate sites)
• Consistency matters: daily use and consistent timing are commonly emphasized for best results

Cycle Length (Common Use Pattern)

• Body-composition–focused protocols are often run for 12–16 weeks minimum
• Some users reassess at 12–16 weeks and continue longer only with monitoring and supervision
• Monitoring: IGF-1 and metabolic markers are commonly tracked during extended use

How to Pair Tesamorelin with Other Peptides

Pairing is usually based on goal:

For stronger GH pulse support (sleep / recovery / recomp):

• Add Ipamorelin (often paired because it supports GH release through a different pathway).
  Stack logic: Tesamorelin = GHRH signal, Ipamorelin = GHRP pathway.

For injury or connective tissue support (without extra GH-axis stimulation):

• Add BPC-157 for tendon/ligament/joint support and gut-support goals.
  Typical informational range: 250–500 mcg daily subQ (often near the area of concern).
• Add TB-500 for broader systemic tissue remodeling support in recovery-focused protocols.

For skin / cosmetic longevity stacks:

• Add GHK-Cu (often discussed for collagen signaling and tissue quality support).

Safety Notes

• Use only with guidance of a licensed medical professional.
• Possible mild effects can include injection-site irritation, flushing, headache, or temporary sleep changes.
• Higher dosing doesn’t necessarily mean better results and can increase side effects.
• Avoid use without clinician approval if pregnant/nursing, under 18, or if you have a complex medical history.
• Because Tesamorelin can raise IGF-1, lab monitoring is commonly recommended during extended protocols.

Legal & Testing Note

Tesamorelin is a prescription medication in many settings and is intended for specific approved clinical use. Tested athletes should assume GH-axis peptides (including GHRH analogs) may be restricted/prohibited under anti-doping rules—verify with your governing body.

Bottom line: Tesamorelin is typically used as a nightly injectable to support natural GH pulses and IGF-1 signaling, with a reputation for visceral fat-focused recomposition and recovery support—best used consistently, paired with strong sleep/training/nutrition habits, and supervised by a qualified clinician.