Cellular energy, mitochondrial support, and healthy aging

NAD⁺ is a critical coenzyme found in every cell, essential for mitochondrial energy production, DNA repair, and metabolic health. Injectable NAD⁺ is used in clinical and wellness settings to rapidly replenish depleted levels—especially during periods of high stress, aging, intense training, or cognitive demand.

Key Benefits

• Supports cellular energy (ATP) production and mitochondrial function
• Helps promote mental clarity and cognitive performance
• Supports exercise recovery and resilience during high output
• Plays a role in DNA repair and cellular stress response (sirtuin activation)
• Commonly used in longevity and metabolic support protocols

Typical Dosage & Administration (Informational)

NAD⁺ dosing varies widely based on goals and individual tolerance.

Common Injection Ranges

• General wellness: 50–100 mg, 2–3× per week
• Loading phase: 100–200 mg daily for 7–10 days
• Athletic recovery / high stress: 200–500 mg, 2–3× per week
• Specialty medical protocols: 500–1,000 mg daily (medical supervision required)

Doses above ~200 mg should be supervised due to increased risk of side effects and liver stress.

Route

• Subcutaneous injection (abdomen or upper arm is common)
• Injection typically takes 30–60 seconds

Timing & Frequency

• Morning use is preferred, as NAD⁺ can be energizing
• Frequency depends on dose:
  • Lower doses → more frequent use
  • Higher doses → longer intervals between injections

IV vs Injection (Quick Overview)

• IV infusion: 250–1,000 mg per session, slow drip over 2–4 hours (clinic-based)
• Subcutaneous injection: smaller doses, more convenient, lower cost, self-administered after training

Both bypass digestion; injections are often chosen for maintenance and convenience, while IVs are used for intensive clinical protocols.

Safety & Tolerability

Common mild effects:

• Injection-site redness, swelling, or tenderness (usually resolves within hours)
• Temporary flushing, nausea, or headache—more common at higher doses

Best practices:

• Rotate injection sites
• Use sterile technique
• Start low and increase gradually
• Avoid exceeding 1,000 mg/day without medical oversight

Monitoring recommended with higher or prolonged dosing:

• Liver enzymes
• Blood pressure
• Symptom tracking

Important Notes

• Injectable NAD⁺ should be used under guidance of a qualified healthcare professional
• Not appropriate for everyone; consult your provider if pregnant, managing chronic conditions, or on medications affecting liver/metabolism

Bottom line: NAD⁺ injections are used to rapidly restore cellular energy and mitochondrial function, with conservative dosing and medical supervision being key to safe, effective use—especially as doses increase.