MOTS-c is a mitochondrial-derived peptide studied for its role in cellular energy regulation and metabolic flexibility. It’s most often used in protocols focused on leaner body composition, improved insulin sensitivity, endurance support, and healthy aging pathways.

Key benefits (what users typically aim for)

• Supports energy metabolism and cellular “fuel switching” (glucose ↔ fat use)
• Helps support insulin sensitivity and healthy glucose handling
• Supports fat oxidation during dieting/training phases (without being a stimulant)
• May support endurance and recovery capacity by promoting efficient energy use

Typical dosage & cycle (informational—not medical advice)

Commonly referenced protocols use:

• 5–15 mg per week, split into 2–3 doses weekly
• Cycle: 2–4 weeks on, then 2–4 weeks off
• Beginner approach: start at the low end and adjust only with clinician guidance

Timing (to match its “metabolic” intent)

Often timed:

• Morning, ideally before food, or
• Before training (especially when aiming to support fat utilization/endurance)

How to use safely

• Use only under guidance of a licensed medical professional. Injection technique, sterility, and sourcing quality matter for safety.
• Do not combine aggressively with fasting, glucose-lowering drugs, or strong insulin sensitizers unless supervised (risk of feeling lightheaded/low blood sugar symptoms).
• Watch for common mild effects: injection-site irritation, temporary fatigue/lethargy, appetite changes.
• Avoid use if pregnant/nursing, under 18, managing a serious medical condition, or with a history of active cancer, unless cleared by your physician.
• Athletes: peptides like MOTS-c may be prohibited by anti-doping rules—verify your governing body before use.

Important note: MOTS-c is widely sold as a research-use-only material in many markets and is not FDA-approved for human use. Always follow applicable laws and professional medical guidance.