BPC-157 (10 mg) — Research Peptide Vial

Overview

BPC-157 is a synthetic pentadecapeptide made up of 15 amino acids (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val). It is described in research literature as a fragment associated with the broader “body protection compound” (BPC) found in gastric juice.

In experimental (non-clinical) research models, BPC-157 is investigated as a tool compound for studying angiogenic signaling, cytoprotective signaling, nitric oxide–associated pathways, growth factor expression, and extracellular matrix remodeling. These properties make it a useful model for exploring molecular repair and regenerative processes under stress conditions in controlled systems.

Product Details

• Product: BPC-157 Research Peptide
• Quantity: 10 mg per vial
• Form: Lyophilized (powder) form for maximum stability during shipping and storage

Biochemical Characteristics

• Sequence (15 aa): Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
• Molecular Formula: C₆₂H₉₈N₁₆O₂₂
• Molecular Weight: 1419.556 g/mol
• PubChem CID: 108101

BPC-157 is a linear peptide (no disulfide bonds). Its proline-rich sequence is frequently discussed in research contexts for contributing to conformational rigidity and reduced susceptibility to proteolytic degradation, supporting stability in aqueous experimental systems.

Research Applications (RUO)

In laboratory research settings, BPC-157 has been used in controlled experimental studies examining:

• Fibroblast proliferation and directional migration
• Endothelial cell growth and angiogenic pattern formation
• Extracellular matrix deposition and remodeling
• Cytoskeletal organization and focal adhesion signaling
• Oxidative stress marker modulation in animal models
• Nitric oxide–associated biochemical pathways

All applications are limited to non-clinical research systems designed to investigate fundamental mechanisms.

Pathway / Mechanistic Context

Mechanistic investigations in preclinical models suggest BPC-157 may influence signaling networks involved in cellular motility and vascular organization. Research discussions include interaction with VEGFR2-associated cascades and downstream nitric oxide–related molecular processes. Additional in-vitro findings describe phosphorylation changes in focal-adhesion signaling proteins involved in cytoskeletal anchoring and cell migration.

Preclinical Research Summary

Published preclinical literature reports investigations of BPC-157 across multiple experimental models. In rodent systems, research has examined vascular recruitment, gastrointestinal tissue integrity, and connective tissue remodeling under controlled laboratory conditions. Additional research has explored stability and tissue-level stress responses in other model systems.

Form & Analytical Testing

Supplied as a lyophilized peptide produced via solid-phase peptide synthesis. Lots are commonly verified using analytical techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS) to confirm molecular identity and purity for reproducible lab workflows.

References

• Sikiric P. et al., Current Pharmaceutical Design (2018) 24(18):2002–2030
• Kang E.A. et al., Digestive Diseases and Sciences (2013) 58:3310–3317
• Seiwerth S. et al., Biomedicines (2018) 6(3):75

Storage & Handling

Store lyophilized material cool, dry, and protected from light according to your lab’s SOP. After reconstitution (e.g., with bacteriostatic water for research workflows), store refrigerated and use within your institution’s validated stability window.